兔抗F9多克隆抗体

Background:

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.

Applications:

ELISA, IHC

Name of antibody:

F9

Immunogen:

Fusion protein of human F9

Full name:

coagulation factor IX

Synonyms：

FIX; P19; PTC; HEMB; THPH8

SwissProt:

P00740

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and human thyroid cancer

IHC Recommend dilution:

25-100