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Background: |
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
EZR |
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Immunogen: |
Fusion protein of human EZR |
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Full name: |
ezrin |
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Synonyms： |
CVL; CVIL; VIL2; HEL-S-105 |
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SwissProt: |
P15311 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and Human esophagus cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
69 kDa |
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WB Positive control: |
Mouse kidney tissue |
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WB Recommended dilution: |
500-2000 |
