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Background: |
The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
EXO5 |
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Immunogen: |
Fusion protein of human EXO5 |
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Full name: |
exonuclease 5 |
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Synonyms: |
DEM1; Exo V; hExo5; C1orf176 |
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SwissProt: |
Q9H790 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human cervical cancer |
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IHC Recommend dilution: |
25-100 |
