兔抗EXD2多克隆抗体

Background:

Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Applications:

ELISA, WB, IHC

Name of antibody:

EXD2

Immunogen:

Fusion protein of human EXD2

Full name:

exonuclease 3'-5' domain containing 2

Synonyms:

EXDL2; C14orf114

SwissProt:

Q9NVH0

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

40-200

WB Predicted band size:

70 kDa

WB Positive control:

Mouse testis tissue lysate

WB Recommended dilution:

200-1000