兔抗ESR2多克隆抗体

Background:

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

Applications:

ELISA, WB, IHC

Name of antibody:

ESR2

Immunogen:

Fusion protein of human ESR2

Full name:

estrogen receptor 2 (ER beta)

Synonyms：

Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA

SwissProt:

Q92731

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and human ovarian cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

59 kDa

WB Positive control:

Mouse brain tissue

WB Recommended dilution:

500-2000