Full name: |
serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
Synonyms: |
EI; LEI; PI2; MNEI; PI-2; HEL57; M/NEI; ELANH2 |
Swissprot: |
P30740 |
Gene Accession: |
BC009015 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. |