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021-54845833/15800441009
相关类别： 抗原
概 述
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Full name: |
snail family transcriptional repressor 2 |
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Synonyms: |
SLUG; WS2D; SLUGH; SLUGH1; SNAIL2 |
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Swissprot: |
O43623 |
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Gene Accession: |
BC014890 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. |
