Background: |
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). |
Applications: |
WB |
Name of antibody: |
ERCC4 |
Immunogen: |
Synthesized peptide derived from internal of human XPF. |
Full name: |
excision repair cross-complementation group 4 |
Synonyms: |
XPF; RAD1; FANCQ; ERCC11 |
SwissProt: |
Q92889 |
WB Predicted band size: |
104 kDa |
WB Positive control: |
293 cells lysate |
WB Recommended dilution: |
500-3000 |