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别 名： REPA2; RPA32; RP-A p32; RP-A p34
相关类别： 抗原
概 述
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Full name: |
replication protein A2, 32kDa |
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Synonyms: |
REPA2; RPA32; RP-A p32; RP-A p34 |
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Swissprot: |
P15927 |
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Gene Accession: |
BC001630 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Replication protein A 32 kDa subunit is a protein that in humans is encoded by theRPA2 gene. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. |
