Background: |
This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. |
Applications: |
ELISA, IHC |
Name of antibody: |
ERAP2 |
Immunogen: |
Synthetic peptide of human ERAP2 |
Full name: |
endoplasmic reticulum aminopeptidase 2 |
Synonyms: |
LRAP; L-RAP |
SwissProt: |
Q6P179 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
10-50 |