Background: |
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009] |
Applications: |
WB |
Name of antibody: |
EPS15(Phospho-Tyr849) |
Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 849 (S-A-Y(p)-P-S) derived from Human Ephrin EPS15. |
Full name: |
epidermal growth factor receptor pathway substrate 15 |
Synonyms: |
AF1P; AF-1P; MLLT5 |
SwissProt: |
P42566 |
WB Predicted band size: |
99 kDa |
WB Positive control: |
Jurkat cells lysates |
WB Recommended dilution: |
500-1000 |