Background: |
This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. |
Applications: |
WB |
Name of antibody: |
EPPIN1 |
Immunogen: |
Fusion protein of human EPPIN1 |
Full name: |
Epididymal protease inhibitor |
Synonyms: |
EPPIN2; EPPIN3; WAP7; WFDC7; dJ461P17.2; CT71; CT72; SPINLW1 |
SwissProt: |
O95925 |
WB Predicted band size: |
15 kDa |
WB Positive control: |
Mouse testis tissue |
WB Recommended dilution: |
500-2000 |