兔抗RAMP3多克隆抗体

Background:

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.

Applications:

ELISA, IHC

Name of antibody:

RAMP3

Immunogen:

Fusion protein of human RAMP3

Full name:

receptor (G protein-coupled) activity modifying protein 3

SwissProt:

O60896

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human ovarian cancer and Human thyroid cancer

IHC Recommend dilution:

50-200