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Background: |
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. |
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Applications: |
WB |
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Name of antibody: |
EPHB1 |
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Immunogen: |
Synthesized peptide derived from C-terminal of human EPHB1. |
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Full name: |
EPH receptor B1 |
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Synonyms： |
ELK; NET; Hek6; EPHT2 |
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SwissProt: |
P54762 |
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WB Predicted band size: |
110 kDa |
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WB Positive control: |
COS7 cells lysate |
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WB Recommended dilution: |
500-3000 |
