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中文名称：兔抗RAF1(Phospho-Ser621) 多克隆抗体
英文名称： Anti-RAF1(Phospho-Ser621) rabbit polyclonal antibody
别 名： NS5; CRAF; Raf-1; c-Raf; CMD1NN
相关类别： 一抗
储 存： 冷冻（-20℃） 避光
宿 主： Rabbit
抗 原： RAF1(Phospho-Ser621)
反应种属： Human Mouse Rat
标记物： Unconjugate
克隆类型： Unconjugate
技术规格
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Background: |
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. |
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Applications: |
WB |
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Name of antibody: |
RAF1(Phospho-Ser621) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 621 (S-A-S(p)-E-P) derived from Human C-RAF. |
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Full name: |
Raf-1 proto-oncogene, serine/threonine kinase |
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Synonyms： |
NS5; CRAF; Raf-1; c-Raf; CMD1NN |
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SwissProt: |
P04049 |
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WB Predicted band size: |
73 kDa |
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WB Positive control: |
Hela cells lysates treated with UV |
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WB Recommended dilution: |
500-1000 |
