Background: |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. |
Applications: |
ELISA, IHC |
Name of antibody: |
EPHA7 |
Immunogen: |
Synthetic peptide of human EPHA7 |
Full name: |
EPH receptor A7 |
Synonyms: |
EHK3; EK11; EHK-3; HEK11 |
SwissProt: |
Q15375 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human prostate cancer |
IHC Recommend dilution: |
25-100 |