Background: |
The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Oct 2009] |
Applications: |
WB |
Name of antibody: |
EPB41(Phospho-Tyr660/418) |
Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y(p)-I-R)derived from Human EPB41. |
Full name: |
erythrocyte membrane protein band 4.1 |
Synonyms: |
HE; EL1; 4.1R |
SwissProt: |
P11171 |
WB Predicted band size: |
97 kDa |
WB Positive control: |
HepG2 cells lysates treated with PMA |
WB Recommended dilution: |
500-1000 |