Background: |
This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. |
Applications: |
WB |
Name of antibody: |
EPAS1 |
Immunogen: |
Peptide sequence around aa.547-551(P-E-E-R-L) derived from HumanHIF2A. |
Full name: |
endothelial PAS domain protein 1 |
Synonyms: |
HLF; MOP2; ECYT4; HIF2A; PASD2; bHLHe73 |
SwissProt: |
Q99814 |
WB Predicted band size: |
96 kDa |
WB Positive control: |
HepG2 and A549 cells lysates |
WB Recommended dilution: |
500-1000 |