Background: |
Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis (PubMed:23108400, PubMed:25278552, PubMed:27767179). Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1 (PubMed:25278552). Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1 (PubMed:23108400). Plays a role in the formation of cilia (PubMed:27767179). Involved in cargo protein localization, such as PKD2, at primary cilia (PubMed:27767179). Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis (By similarity). |
Applications: |
ELISA, WB |
Name of antibody: |
ENTR1 |
Immunogen: |
Fusion protein of human ENTR1 |
Full name: |
endosome associated trafficking regulator 1 |
Synonyms: |
NY-CO-3; SDCCAG3 |
SwissProt: |
Q96C92 |
WB Predicted band size: |
46 kDa |
WB Positive control: |
Hela cells |
WB Recommended dilution: |
500-2000 |