POLR1C 抗原（重组蛋白）

Full name:

RNA polymerase I subunit C

Synonyms:

AC40; RPA5; TCS3; HLD11; RPA39; RPA40; RPAC1; RPC40

Swissprot:

O15160

Gene Accession:

BC008863

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.