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中文名称： POR 抗原（重组蛋白）
英文名称： POR Antigen (Recombinant Protein)
别 名： cytochrome p450 oxidoreductase; CPR; CYPOR; P450R
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
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Full name: |
cytochrome p450 oxidoreductase |
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Synonyms: |
CPR; CYPOR; P450R |
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Swissprot: |
P16435 |
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Gene Accession: |
BC034277 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. |
