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英文名称： NDUFA12 Antigen (Recombinant Protein)
概 述
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Full name: |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 |
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Synonyms: |
B17.2; DAP13 |
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Swissprot: |
Q9UI09 |
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Gene Accession: |
BC005936 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants. |
