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中文名称： 兔抗PTPRJ多克隆抗体
英文名称： Anti-PTPRJ rabbit polyclonal antibody
别 名： DEP1, SCC1, CD148, HPTPeta, R-PTP-ETA
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： PTPRJ
反应种属： Human, Mouse
标 记 物： Unconjugate
克隆类型：rabbit polyclonal
技术规格
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Background: |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PTPRJ |
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Immunogen: |
Synthetic peptide of human PTPRJ |
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Full name: |
Protein tyrosine phosphatase, receptor type, J |
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Synonyms： |
DEP1, SCC1, CD148, HPTPeta, R-PTP-ETA |
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SwissProt: |
Q12913 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human breast cancer and Human liver cancer |
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IHC Recommend dilution: |
25-100 |
