购物车
帮助
021-54845833/15800441009
中文名称：兔抗PTPN11多克隆抗体
英文名称： Anti-PTPN11 rabbit polyclonal antibody
别 名： CFC, NS1, SHP2, BPTP3, PTP2C, PTP-1D, SH-PTP2, SH-PTP3
抗 原： PTPN11
储 存： 冷冻（-20℃）
宿 主： Rabbit
相关类别： 一抗
反应种属： Human, Mouse, Rat
标记物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
|
Background: |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. |
|
Applications: |
ELISA, WB |
|
Name of antibody: |
PTPN11 |
|
Immunogen: |
Fusion protein of human PTPN11 |
|
Full name: |
protein tyrosine phosphatase, non-receptor type 11 |
|
Synonyms： |
CFC, NS1, SHP2, BPTP3, PTP2C, PTP-1D, SH-PTP2, SH-PTP3 |
|
SwissProt: |
Q06124 |
|
ELISA Recommended dilution: |
1000-5000 |
|
WB Predicted band size: |
68 kDa |
|
WB Positive control: |
NIH/3T3 cells |
|
WB Recommended dilution: |
200-1000 |
