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  • MYD88抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW19379
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: MYD88抗原(重组蛋白)

英文名称: MYD88 Antigen (Recombinant Protein)

别     名:  MYD88D

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述 

Full length fusion protein

技术规格

Full name:

myeloid differentiation primary response 88

Synonyms:

MYD88D

Swissprot:

Q99836

Gene Accession:

BC013589

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.