兔抗EIF4EBP1(Ab-64) 多克隆抗体

Background:

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation.

Applications:

WB, IHC

Name of antibody:

EIF4EBP1(Ab-64)

Immunogen:

Synthesized non-phosphopeptide derived from human 4E-BP1 around the phosphorylation site of serine 65 (R-N-S(p)-P-V).

Full name:

eukaryotic translation initiation factor 4E binding protein 1

Synonyms：

BP-1; 4EBP1; 4E-BP1; PHAS-I

SwissProt:

Q13541

IHC positive control:

Human colon carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

13 kDa

WB Positive control:

Jurkat cells treated with Insulin (0.01U/ml, 15mins) lysate

WB Recommended dilution:

500-3000