中文名称: 兔抗GTF2A2多克隆抗体
英文名称: Anti-GTF2A2 rabbit polyclonal antibody
别 名: general transcription factor IIA subunit 2; TF2A2; TFIIA; T18745; TFIIAS; HsT18745; TFIIA-12; TFIIA-gamma
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: GTF2A2
反应种属: Human, Mouse, Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
Background:
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).
Applications:
ELISA, IHC
Name of antibody:
GTF2A2
Immunogen:
Fusion protein of human GTF2A2
Full name:
general transcription factor IIA subunit 2
Synonyms:
TF2A2; TFIIA; T18745; TFIIAS; HsT18745; TFIIA-12; TFIIA-gamma
SwissProt:
P52657
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human liver cancer and Human tonsil
IHC Recommend dilution:
30-150
技术规格