Background: |
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
EEF1D |
Immunogen: |
Fusion protein of human EEF1D |
Full name: |
eukaryotic translation elongation factor 1 delta |
Synonyms: |
EF1D; EF-1D; FP1047 |
SwissProt: |
P29692 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human thyroid cancer and Human ovarian cancer |
IHC Recommend dilution: |
50-300 |
WB Predicted band size: |
31 kDa |
WB Positive control: |
A549, A172 and HepG2 cell lysates |
WB Recommended dilution: |
1000-5000 |