中文名称: 兔抗MLANA多克隆抗体
英文名称: Anti-MLANA rabbit polyclonal antibody
别 名: MART1; MART-1
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: MLANA
反应种属: Human
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
Melan-A (also designated MART-1) is a melanocyte differentiation antigen that is specific to melanomas, melanocyte cell lines and retina. Melan-A peptide is recognized by most HLA-A2-restricted tumor-specific tumor-infiltrating lymphocytes in patients with melanoma. Antimelanoma cytotoxic T lymphocytes can be generated with a Melan-A peptide, implicating Melan-A as a potential candidate for antigen-specific immunotherapy in melanoma patients. Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. |
Applications: |
ELISA, IHC |
Name of antibody: |
MLANA |
Immunogen: |
Synthetic peptide of human MLANA |
Full name: |
melan-A |
Synonyms: |
MART1; MART-1 |
SwissProt: |
Q16655 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human esophagus cancer |
IHC Recommend dilution: |
40-250 |