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    • 品牌 : 通蔚生物
    • 目录号 : TW19009
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称:  兔抗MLANA多克隆抗体


英文名称:  Anti-MLANA rabbit polyclonal antibody


别      名:  MART1; MART-1


相关类别:  一抗


储      存:  冷冻(-20℃)


宿      主:  Rabbit


抗      原:  MLANA


反应种属:  Human


标  记 物:  Unconjugate


克隆类型  rabbit polyclonal


技术规格

Background:

Melan-A (also designated MART-1) is a melanocyte differentiation antigen that is specific to melanomas, melanocyte cell lines and retina. Melan-A peptide is recognized by most HLA-A2-restricted tumor-specific tumor-infiltrating lymphocytes in patients with melanoma. Antimelanoma cytotoxic T lymphocytes can be generated with a Melan-A peptide, implicating Melan-A as a potential candidate for antigen-specific immunotherapy in melanoma patients. Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.

Applications:

ELISA, IHC

Name of antibody:

MLANA

Immunogen:

Synthetic peptide of human MLANA

Full name:

melan-A

Synonyms:

MART1; MART-1

SwissProt:

Q16655

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

40-250