Background: |
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]). |
Applications: |
ELISA, IHC |
Name of antibody: |
EDEM3 |
Immunogen: |
Synthetic peptide of human EDEM3 |
Full name: |
ER degradation enhancing alpha-mannosidase like protein 3 |
Synonyms: |
C1orf22 |
SwissProt: |
Q9BZQ6 |
ELISA Recommended dilution: |
500-1000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
25-100 |