Background: |
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]). |
Applications: |
ELISA, IHC |
Name of antibody: |
EDEM2 |
Immunogen: |
Fusion protein of human EDEM2 |
Full name: |
ER degradation enhancing alpha-mannosidase like protein 2 |
Synonyms: |
C20orf31; C20orf49; bA4204.1 |
SwissProt: |
Q9BV94 |
ELISA Recommended dilution: |
500-1000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |