兔抗U2AF2多克隆抗体

Background:

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.

Applications:

ELISA, IHC

Name of antibody:

U2AF2

Immunogen:

Fusion protein of human U2AF2

Full name:

U2 small nuclear RNA auxiliary factor 2

Synonyms:

U2AF65

SwissProt:

P26368

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

25-100