Background: |
Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. |
Applications: |
ELISA, IHC |
Name of antibody: |
DUSP13 |
Immunogen: |
Fusion protein of human DUSP13 |
Full name: |
dual specificity phosphatase 13 |
Synonyms: |
BEDP; MDSP; TMDP; SKRP4; DUSP13A; DUSP13B |
SwissProt: |
Q9UII6 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer and human brain |
IHC Recommend dilution: |
50-200 |