中文名称:兔抗DTWD1多克隆抗体
Background: |
Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
DTWD1 |
Immunogen: |
Full length fusion protein |
Full name: |
DTW domain containing 1 |
Synonyms: |
MDS009 |
SwissProt: |
Q8N5C7 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human thyroid cancer and human colorectal cancer |
IHC Recommend dilution: |
20-100 |