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中文名称： 兔抗DPYD多克隆抗体
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Background: |
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
DPYD |
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Immunogen: |
Full length fusion protein |
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Full name: |
dihydropyrimidine dehydrogenase |
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Synonyms： |
DHP; DPD; DHPDHASE |
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SwissProt: |
Q12882 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil |
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IHC Recommend dilution: |
25-100 |
