中文名称:LDB1抗原(重组蛋白)
英文名称: LDB1 Antigen (Recombinant Protein)
别 名: NLI; CLIM2; LDB-1; CLIM-2
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to a region derived from 212-411 amino acids of human LDB1 |
Full name: |
LIM domain binding 1 |
Synonyms: |
NLI; CLIM2; LDB-1; CLIM-2 |
Swissprot: |
Q86U70 |
Gene Accession: |
BC000482 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity). |