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Background: |
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. |
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Applications: |
WB, IHC |
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Name of antibody: |
DOK1 (phospho-Tyr398) |
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Immunogen: |
Synthetic peptide of human DOK1 (phospho-Tyr398) |
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Full name: |
docking protein 1, 62kDa (downstream of tyrosine kinase 1) (phospho-Tyr398) |
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Synonyms： |
P62DOK |
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SwissProt: |
Q99704 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
62 kDa |
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WB Positive control: |
K562 cells treated with H2O2 |
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WB Recommended dilution: |
500-1000 |
