Background: |
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. |
Applications: |
WB |
Name of antibody: |
DNM1(Phospho-Ser774) |
Immunogen: |
Peptide sequence around phosphorylation site of serine 774 (R-R-S(p)-P-T) derived from Dynamin-1. |
Full name: |
dynamin 1 |
Synonyms: |
DNM |
SwissProt: |
Q05193 |
WB Predicted band size: |
97 kDa |
WB Positive control: |
Rat brain tissue lysates |
WB Recommended dilution: |
500-1000 |