兔抗DMD多克隆抗体

Background:

The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level.

Applications:

ELISA, IHC

Name of antibody:

DMD

Immunogen:

Fusion protein of human DMD

Full name:

dystrophin

Synonyms：

BMD; CMD3B; MRX85; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272

SwissProt:

P11532

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human breast cancer and Human brain

IHC Recommend dilution:

25-100