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中文名称：FARP2抗原（重组蛋白）
英文名称： FARP2 Antigen (Recombinant Protein)
别 名： FIR; FRG; PLEKHC3
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 1-200 amino acids of human FARP2 |
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Full name: |
FERM, ARH/RhoGEF and pleckstrin domain protein 2 |
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Synonyms: |
FIR; FRG; PLEKHC3 |
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Swissprot: |
O94887 |
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Gene Accession: |
BC021301 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity). |
