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021-54845833/15800441009
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Background: |
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
DLD |
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Immunogen: |
Fusion protein of human DLD |
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Full name: |
dihydrolipoamide dehydrogenase |
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Synonyms： |
E3; LAD; DLDD; DLDH; GCSL; PHE3 |
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SwissProt: |
P09622 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human brain and Human prostate cancer |
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IHC Recommend dilution: |
50-200 |
