Background: |
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene. |
Applications: |
IHC, IF |
Name of antibody: |
DLC1 |
Immunogen: |
Synthesized peptide derived from internal of human RHG07. |
Full name: |
DLC1 Rho GTPase activating protein |
Synonyms: |
HP; ARHGAP7; STARD12; p122-RhoGAP |
SwissProt: |
Q96QB1 |
IHC positive control: |
Human prostate carcinoma tissue |
IHC Recommend dilution: |
50-100 |
IF positive control: |
A549 cells |
IF Recommend dilution: |
100-500 |