Background: |
This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. |
Applications: |
ELISA, WB |
Name of antibody: |
DIRAS3 |
Immunogen: |
Fusion protein of human DIRAS3 |
Full name: |
DIRAS family GTPase 3 |
Synonyms: |
ARHI; NOEY2 |
SwissProt: |
O95661 |
ELISA Recommended dilution: |
5000-10000 |
WB Predicted band size: |
26 kDa |
WB Positive control: |
Rat brain tissue and Rat liver tissue lysates |
WB Recommended dilution: |
200-1000 |