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  • DHFR抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW18581
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称:DHFR抗原(重组蛋白)

英文名称: DHFR Antigen (Recombinant Protein)

别      名: DYR; DHFRP1

储      存: 冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to a region derived from 2-187 amino acids of human DHFR


技术规格:

Full name:

dihydrofolate reductase

Synonyms:

DYR; DHFRP1

Swissprot:

P00374

Gene Accession:

BC000192

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene.