中文名称:ZFYVE27抗原(重组蛋白)
英文名称: ZFYVE27 Antigen (Recombinant Protein)
别 名: SPG33; PROTRUDIN
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to a region derived from 212-411 amino acids of human ZFYVE27 |
Full name: |
zinc finger FYVE-type containing 27 |
Synonyms: |
SPG33; PROTRUDIN |
Swissprot: |
Q5T4F4 |
Gene Accession: |
BC030621 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. |