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中文名称：UBD抗原（重组蛋白）
英文名称： UBD Antigen (Recombinant Protein)
别 名： FAT10; UBD-3; GABBR1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 1-165 amino acids of human UBD |
|
Full name: |
ubiquitin D |
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Synonyms: |
FAT10; UBD-3; GABBR1 |
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Swissprot: |
O15205 |
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Gene Accession: |
BC012472 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types. |
