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相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 1-200 amino acids of human TTC12 |
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Full name: |
tetratricopeptide repeat domain 12 |
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Synonyms: |
TPARM |
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Swissprot: |
Q9H892 |
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Gene Accession: |
BC032355 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
TTC12 (tetratricopeptide repeat domain 12), also known as TPARM, is a 705 amino acid cytoplasmic protein containing a TPR repeat domain and three armadillo repeat motifs. TTC12 is expressed in testis, prostate, lung, germinal center B cells, neuroblastoma, teratocarcinoma, colon cancer and gastric cancer. The gene encoding TTC12 is located in a region of human chromosome 11 that is commonly deleted in a variety of cancers, therefore, it is considered a candidate tumor suppressor gene. Human chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. |
