英文名称: TSEN2 Antigen (Recombinant Protein)
别 名: SEN2; PCH2B; SEN2L
储 存: 冷冻(-20℃)
相关类别: 抗原
Fusion protein corresponding to a region derived from 266-465 amino acids of human TSEN2 |
Full name: |
tRNA splicing endonuclease subunit 2 |
Synonyms: |
SEN2; PCH2B; SEN2L |
Swissprot: |
Q8NCE0 |
Gene Accession: |
BC004178 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. |