中文名称:TRMT12抗原(重组蛋白)
英文名称: TRMT12 Antigen (Recombinant Protein)
别 名: TYW2; TRM12
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to a region derived from 249-448 amino acids of human TRMT12 |
Full name: |
tRNA methyltransferase 12 homolog |
Synonyms: |
TYW2; TRM12 |
Swissprot: |
Q53H54 |
Gene Accession: |
BC011713 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006). |