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中文名称：PRKAG2抗原（重组蛋白）
英文名称： PRKAG2 Antigen (Recombinant Protein)
别 名： AAKG; CMH6; WPWS; AAKG2; H91620p
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 370-569 amino acids of human PRKAG2 |
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Full name: |
protein kinase AMP-activated non-catalytic subunit gamma 2 |
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Synonyms: |
AAKG; CMH6; WPWS; AAKG2; H91620p |
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Swissprot: |
Q9UGJ0 |
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Gene Accession: |
BC020540 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
